Journal Article IMPULSE-2026-00003

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A Monte Carlo dose engine for fast neutron therapy and boron neutron capture therapy for matRad

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2025
IOP Publ. Bristol

Biomedical physics & engineering express 11(6), 065023 () [10.1088/2057-1976/ae12f7]

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Abstract: Objective: The purpose of the work presented here was to enable easy access to Monte Carlo dosecalculation for both fast neutron therapy and boron neutron capture therapy for research purposes.The dose calculation approach was especially intended to hold high customization potential forindividual user applications. Approach: The dose engine is based on the Monte Carlo code MCNP. Itis integrated into the MATLAB-based open source research treatment planning software matRad asmodular component. Main results: Total dose calculation is enabled for both fast neutron therapyand boron neutron capture therapy on patient CTdata. The evaluation of the dose distribution ispossible using the matRad graphical user interface and dose volume histograms. Customizationoptions are provided for advanced users. Significance: The open source treatment planning softwareallows easy access to highly accurate Monte Carlo dose calculation for research projects.

Keyword(s): Health and Life (1st) ; Medicine (2nd)

Classification:

Note: Please add funding information: BMFTR ErUMPro project FKZ 05K22WO6 and DFG Project No. 443188743.

Contributing Institute(s):
  1. MEDAPP (MEDAPP)
Research Program(s):
  1. GRK 2274 - GRK 2274: Fortgeschrittene Medizinische Physik für bildgeführte Krebstherapie (299102935) (299102935)
Experiment(s):
  1. Medical Application Facility (SR10)

Database coverage:
Medline ; Clarivate Analytics Master Journal List ; Emerging Sources Citation Index ; IF < 5 ; JCR ; National-Konsortium ; SCOPUS ; Web of Science Core Collection
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 Record created 2026-01-21, last modified 2026-01-28


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