Journal Article IMPULSE-2023-00183

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A new Multi Leaf Collimator for the fission neutron therapy facility at FRM II

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2023
North-Holland Publ. Co. Amsterdam

Nuclear instruments & methods in physics research / Section A 1057, 168717 - () [10.1016/j.nima.2023.168717]

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Abstract: As a part of the general upgrade program of the fission neutron therapy facility MEDAPP at the research reactor FRM II, a newly designed, electronically operated Multi Leaf Collimator (MLC) was introduced. The design of the new collimator was optimized in order to increase dose output and to allow patient positioning closer to the collimator. The new collimator allows divergent and convergent beam shaping in order to maximize the effective area of the fission source used for irradiation. In comparison to the old MLC, the radiation dose for the staff is reduced by the motorized operation of the new MLC. The advanced beam shaping abilities of the new collimator are investigated by a comparison with depth dose curves and beam profiles of the old MLC. For the separation of neutron and gamma dose deposition in water, the two chamber dosimetry method recommended for mixed field dosimetry was applied. A re-calibration of the set of ionization chambers used for dosimetry in mixed neutron-gamma radiation fields at FRM II was performed. The calibration was done in a reference neutron field in a low scattering environment. An overall increased dose output as intended by the design of the new MLC was shown. Also, improved dosimetric characteristics of the treatment field due to the optimized beam shaping abilities of the new MLC were demonstrated. In the calibration measurements of the magnesium ionization chamber used in the two chamber method, an unexpected increase of the neutron sensitivity by a factor of 8 was measured. The new MLC will enable more conformal dose delivery to the target volume in patients and therefore help to reduce healthy tissue damage by the application of neutron radiation.

Keyword(s): Instrument and Method Development (1st) ; Medicine (2nd)

Classification:

Contributing Institute(s):
  1. MEDAPP (MEDAPP)
  2. CNSI (RPHYSICS ; CNSI)
Research Program(s):
  1. GRK 2274 - GRK 2274: Fortgeschrittene Medizinische Physik für bildgeführte Krebstherapie (299102935) (299102935)
Experiment(s):
  1. Medical Application Facility (SR10)

Appears in the scientific report 2023
Database coverage:
Medline ; Clarivate Analytics Master Journal List ; Current Contents - Engineering, Computing and Technology ; Current Contents - Physical, Chemical and Earth Sciences ; Ebsco Academic Search ; Essential Science Indicators ; IF < 5 ; JCR ; NationallizenzNationallizenz ; SCOPUS ; Science Citation Index Expanded ; Web of Science Core Collection
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Institute Collections > RPHYSICS
Institute Collections > MEDAPP
Publications database

 Record created 2023-10-10, last modified 2023-10-12


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