Dissertation / PhD Thesis

IMPULSE-2023-00054

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Development and Validation of a 3D Neutron Therapy Treatment Planning Software for FRM II

Sommer, L.MLZ*

2023
Munich

Abstract: Two dose calculation approaches for mixed neutron-gamma fields applied in radiation oncology were investigated. The main goal was to enable 3D dose calculation for the fission based fast neutron therapy unit MEDAPP at the research reactor FRM II. While the investigated pencil beam kernels enable time efficient dose calculation on a patient CT, the considered Monte Carlo approach provides higher reliability in handling tissue heterogeneities and the option to model biological effects of neutron radiation. Verification measurements in water showed overall good agreement.

Keyword(s): Health and Life (1st) ; Medicine (2nd)

Note: Dissertation, TU Munich, 2022

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Contributing Institute(s):

1. MEDAPP (MEDAPP)
2. Technische Universität München (TUM)

Research Program(s):

1. GRK 2274 - GRK 2274: Fortgeschrittene Medizinische Physik für bildgeführte Krebstherapie (299102935) (299102935)

Experiment(s):

1. Medical Application Facility (SR10)

Appears in the scientific report 2023

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